CONCERNING THE NATURALLY OCCURRING PORPHYRINS. V. PORPHYRINS OF THE FECES 12
نویسندگان
چکیده
منابع مشابه
Concerning the Naturally Occurring Porphyrins
Evidence for a dualism of the porphyrins in nature has been repeatedly presented by Hans Fischer (1, 2, 3). This means that both plant and animal organisms are capable of the formation of porphyrins of two isomeric series, those corresponding to aetioporphyrin III, including hemoglobin and chlorophyll, and those of the aetioporphyrin I type, the function of whose representatives is as yet very ...
متن کاملPlasma porphyrins in the porphyrias.
BACKGROUND As an aid in the diagnosis and management of porphyria we have developed a method to fractionate and quantify plasma porphyrins and have evaluated its use in various porphyrias. METHODS We used HPLC with fluorometric detection to measure plasma concentrations of uroporphyrin I and III, heptacarboxyl III, hexacarboxyl III, pentacarboxyl III, and coproporphyrin I and III. We studied ...
متن کاملThe porphyrins of acute porphyria. The detection of hitherto unrecognized porphyrins.
Waldenstr6m (1934) reported the natural occurrence inacute porphyria ofauroporphyrinIII, butWatson, Schwartz & Hawkinson (1945) and Prunty (1946) found evidence for the belief that this Waldenstr8m porphyrin was a mixture of a large proportion of uroporphyrin I with a smaller amount of a type III porphyrin. The observations of Watson et al. (1945) also indicated the presence in the urine ofporp...
متن کاملIntracellular trafficking of porphyrins.
Hemes are porphyrins that play a critical role in diverse biological processes. Heme synthesis culminates in the mitochondrial matrix, but the eight-step biosynthetic pathway is spatially shared between the mitochondria and cytoplasm. A recent paper describes the nature of the transporter that translocates the heme precursor coproporphyrinogen III into the mitochondria for heme synthesis. The i...
متن کاملOxidation of ferric porphyrins.
Characterization of heme oxidation products falls naturally into two categories: species resulting from electron transfer, and in vivo and in vitro heme degradation products formed by oxidative addition or cleavage. In the former, we propose to include the intermediates appearing during the catalytic cycles of catalase (Cat), horseradish peroxidase (HRP), and cytochrome c peroxidase; the latter...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1937
ISSN: 0021-9738
DOI: 10.1172/jci100865